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Class Projects

Amber Leigh Ortiz, Project List, 1/27/2012

Current Lab Work: Project 1

Can mNPs be endocytosed in Breast Cancer cells as a Cancer Therapy Using an AMF to cause hyperthermia?

• Will the cell take up the mNPs?
• What surface characteristic will increase the possibility of endocytosis?

• Can the cells be killed by heat?
• What temperature?
• How long?

• Will the AMF increase the residual heat with the help of the mNPs?

• How are the mNPs taken up by the cells?
• Endosomes
• Test using EEA1 antibody
• Lysosomes
• Test using LysoTracker

• Do the mNPs have any inherent toxicity?
• At what concentrations?
• Time?

• How long must the cells incubate with the mNPs?
• What happened overtime?
• 30min --> 24hrs

• Will targeting be used?
• If not why?
• How? What can/will be used?

Future Directions:

• Clinical, how will treatment be applied?

Outreach/ the "NEW" Freshmen Summer Bridge Program: Project 2

Problems:

• Increase freshmen retention rates

• Math and Science requirements are low in the High School curriculum
• Math (Science in some cases) is now always required in the senior year

• Increase interest in STEM Fields

• Prepare HS students for college course rigor

• Obtain network of friends/support prior to beginning college

• Students need better advisement
• Students able to become "pre-major" status through program
• Able to cater advising early on

• Current Freshmen Summer Bridge Programs
• 3 months (short)
• Not full length college courses
• No lab experience

My Idea:

• Many points discussed above

• Students will be a part of a yearlong program
• Starting in their Senior year and ending just before beginning their first year in college

• Students will obtain research experience
• Help with finding specific interests in science and better understanding

• College Credit - Participate in Math, Science, and English course
• Help in bridging into the course rigor

• Help students to pick proper freshmen course list

• Students obtain mentors
• Professor/PI
• Upperclassmen students help them through the process
• Best classes
• Best professors
• Best tutors
• Best TAs

• Participate in mini-symposium presented by different (participating) departments
• Students learn "What is out there?"

• Program provides tutors for students during the program

• Students learn about the University
• CAPs
• Libraries
• Other Resources

• Students are tracked to understand program efficacy

Program Eligibility: ?

• Personal Essays
• Future Goals
• Why they want to be a part of the program

• HS Recommendation

• Grades?

• Must have "on-track" graduation status with HS

• Must be planning to apply to college
• Preferably State school?
• Nationally?
• Will the program help in this application process